Pycnogenol (French Maritime Pine Bark Extract)

Circulation & antioxidants

Function & benefits

A standardized extract of French maritime pine bark rich in procyanidins (OPCs); it helps support nitric oxide production in the artery lining, supporting flexible blood vessels and microcirculation, and helps stabilize collagen and elastin fibres.

Dosage & how to use

Recommended dose	100–200 mg daily (65–75% procyanidins)
Best time to take	With breakfast and lunch and a glass of water
Frequency	Split into two doses

Best forms to choose

The registered Pycnogenol® extract, standardized to 65–75% procyanidins, or an equivalent maritime pine bark extract.

Important warnings

May cause stomach upset or brief dizziness on an empty stomach

Avoid it in the first trimester of pregnancy and consult a doctor afterwards

Consult a doctor if you have an autoimmune disease

Drug interactions

It widens blood vessels and inhibits platelets; take care with blood thinners, anticoagulants and blood pressure medication. It may lower blood sugar slightly.

View in the supplements guide

Related supplements

Scientific references

Rohdewald P. Int J Clin Pharmacol Ther 2002 (review) — PMID: 11996210

📚 Published sources and research: European Food Safety Authority (EFSA) • National Institutes of Health (NIH - ODS) • PubMed / Cochrane databases

Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)

⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.