Grape Seed Extract (95% OPC)
Circulation & antioxidantsFunction & benefits
An extract rich in proanthocyanidins (OPCs), plant antioxidants that help protect collagen fibres in the skin and blood vessel walls; studies suggest it supports veins and circulation, eases heavy, swollen legs after long sitting, and supports a radiant, even skin tone.
Dosage & how to use
| Recommended dose | 100–300 mg daily |
| Best time to take | After breakfast or lunch |
| Frequency | Once daily |
Best forms to choose
Grape seed extract standardised to 95% proanthocyanidins (OPCs), in capsules or tablets.
Important warnings
Stop two weeks before surgery because of its mild blood-thinning effect
Avoid during pregnancy and breastfeeding, as safety data are insufficient
Drug interactions
Use with care alongside blood thinners and antiplatelet drugs (warfarin, aspirin, clopidogrel), as the risk of bleeding may increase.
Related supplements
- Pycnogenol (French Maritime Pine Bark Extract)Circulation & antioxidants
- Daily MultivitaminsGeneral health & immunity
- Omega-3 Fish OilGeneral & heart health
- Vitamin D3 (Cholecalciferol)General health & bones
Scientific references
- Sano A et al. J Sci Food Agric 2013 — PMID: 22752876
- Yamakoshi J et al. Phytother Res 2004 — PMID: 15597304
Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)
⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.