Nicotinamide Riboside (NR, Niagen®)
Cellular energy & focusFunction & benefits
A form of vitamin B3 authorised in the EU as a novel food (nicotinamide riboside chloride) that cells turn into NAD+, which the mitochondria need to produce energy; a double-blind trial suggests it safely raised NAD+ levels in middle-aged and older adults.
Dosage & how to use
| Recommended dose | Up to 300 mg daily (the maximum authorised for adults in the EU) |
| Best time to take | In the morning with breakfast or lunch |
| Frequency | Once daily |
Best forms to choose
Nicotinamide riboside chloride (such as Niagen®) in capsules.
Important warnings
Authorised for adults only; not for use during pregnancy or breastfeeding
It does not cause the skin flushing known from nicotinic acid
Count the niacin in all your supplements
Drug interactions
No important drug interactions have been reported at the authorised doses.
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Scientific references
- EFSA Journal 2019;17(8):5775 (safety of nicotinamide riboside chloride as a novel food)
- Martens CR et al. Nat Commun 2018 — PMID: 29599478
Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)
⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.