PQQ (Pyrroloquinoline Quinone Disodium Salt)
Cellular energy & focusFunction & benefits
A redox cofactor that studies suggest can stimulate the formation of new mitochondria in cells through the CREB pathway and PGC-1alpha, helping protect brain and heart cells from oxidative stress and support mental energy.
Dosage & how to use
| Recommended dose | 10–20 mg daily (EU authorised maximum 20 mg) |
| Best time to take | With breakfast |
| Frequency | Once daily |
Best forms to choose
Fermented PQQ disodium salt authorised as a novel food in the EU (such as BioPQQ®), often combined with CoQ10.
Important warnings
Stick to the EU authorised limit of 20 mg a day at most
Its safety has not been established in pregnancy, breastfeeding or under the age of 18
Drug interactions
No major drug interactions have been reported at the authorised doses.
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Scientific references
- EFSA Journal 2017;15(11):5058 (safety of PQQ disodium salt as a novel food)
- Harris CB et al. J Nutr Biochem 2013 — PMID: 24231099
Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)
⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.