Magnesium L-Threonate (Magtein®)
Focus & memoryFunction & benefits
A form of magnesium designed to raise magnesium levels in the brain; magnesium contributes to the normal function of the nervous system, normal psychological function and the reduction of tiredness and fatigue (EFSA-authorised claims), an animal study suggests it supports learning and memory, and a recent clinical trial suggests it improves sleep quality and daytime functioning.
Dosage & how to use
| Recommended dose | 1000–2000 mg of Magtein® daily (providing about 72–144 mg of elemental magnesium) |
| Best time to take | One dose with lunch and one an hour before bed |
| Frequency | Split into two doses |
Best forms to choose
Branded magnesium L-threonate (Magtein®), in capsules or powder.
Important warnings
The EFSA upper limit for magnesium from supplements is 250 mg a day; count the magnesium in all your supplements
Use with care if you have kidney failure, because the kidneys clear magnesium from the body
It is gentler on the gut than other forms of magnesium, but may cause drowsiness or a mild headache
Drug interactions
It reduces the absorption of tetracycline and quinolone antibiotics and osteoporosis drugs (bisphosphonates), so take it at least two hours apart from them.
Related supplements
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- Lion's Mane Mushroom (Hericium erinaceus)Focus & memory
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- Alpha-GPC (L-Alpha Glycerylphosphorylcholine)Focus & memory
Scientific references
- Slutsky I et al. Neuron 2010 — PMID: 20152124
- Hausenblas HA et al. Sleep Med X 2024 — PMID: 39252819
Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)
⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.