WiBo Health

Oral Hyaluronic Acid (Sodium Hyaluronate)

Joints & skin

Function & benefits

A molecule that holds large amounts of water and occurs naturally in the skin and joint fluid; a double-blind trial and a recent analysis suggest that taking it by mouth supports skin hydration and elasticity and softens the look of fine wrinkles, and it is also used to support supple, comfortable joints.

Dosage & how to use

Recommended dose100–200 mg daily
Best time to takeIn the morning or with lunch, with a large glass of water
FrequencyOnce daily

Best forms to choose

Low- to medium-molecular-weight sodium hyaluronate made by fermentation, in capsules.

Important warnings

Safe and well tolerated in adults

Not recommended during pregnancy, breastfeeding or for children, as data are insufficient

Drink enough water throughout the day

Drug interactions

No important drug interactions have been reported.

View in the supplements guide

Related supplements

Scientific references

  1. Hsu TF et al. Nutrients 2021 — PMID: 34203487
  2. Amin P et al. J Drugs Dermatol 2025 — PMID: 40911749
📚 Published sources and research: European Food Safety Authority (EFSA) • National Institutes of Health (NIH - ODS) • PubMed / Cochrane databases

Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)

⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.