Pepperoni Pizza (Slice)
The richest pizza: a slice of dough topped with mozzarella and cured pepperoni. Its glycemic index is medium (60) thanks to its fat, but it is loaded with calories, saturated fat and sodium.
Glycemic index
Glycemic load
Calories
Protein
💡 Smart Nutritional Guidance
Consumption advice
Stick to one slice and drink plenty of water to balance the salt; avoid sugary soft drinks with it, as they double the meal's sugar load.
Best preparation methods
Blot the oil on top of the slice with a paper napkin before eating to remove a good amount of the excess fat.
Important Nutritional Note
For people with diabetes or insulin resistance, it is always recommended to consider the total glycemic load (GL) of the meal rather than relying on the glycemic index alone.
Nutrition facts
| Nutrient | Per 100 g | Per typical portion (100 g) |
|---|---|---|
| Calories | 300 kcal | 300 kcal |
| Protein | 13 g | 13 g |
| Carbohydrate | 33 g | 33 g |
| Available carbohydrate | 31 g | 31 g |
| Fat | 13 g | 13 g |
| Dietary fibre | 2 g | 2 g |
The typical portion is approximate, for comparison purposes.
Comparison & smarter alternatives
Among the foods in Fast food with a glycemic index (7), it ranks 7 (lowest first).
Smart alternatives from the same family:
- Subway Chicken TeriyakiGlycemic index 52
- Big MacGlycemic index 55
- Margherita Pizza (Slice)Glycemic index 60
Frequently asked questions
Is Pepperoni Pizza (Slice) good for weight loss?
It can fit a balanced plan with portion control: a 100 g portion gives 300 kcal, and what matters most is your total daily intake and the rest of the meal.
How does Pepperoni Pizza (Slice) affect blood sugar?
Its glycemic index is 60 (Medium), a clinically reviewed estimate rather than a laboratory measurement. A typical 100 g portion has a glycemic load of 18.6 (Medium), so it is best combined with protein or fibre-rich vegetables.
What is the nutritional value of a typical portion of Pepperoni Pizza (Slice)?
A typical 100 g portion of Pepperoni Pizza (Slice) provides about 300 kcal, 13 g protein, 33 g carbohydrate, 13 g fat and 2 g fibre.
Reviewed by the WiBo Health medical team · Last reviewed 13 October 2026
Disclaimer: This guidance is for nutritional lifestyle orientation and does not constitute a diagnostic medical device under EU Regulation MDR 2017/745.