WiBo Health

Vitex (Chasteberry, Agnus Castus)

Women's health & hormonal balance

Function & benefits

The fruit of a Mediterranean shrub that acts on dopamine receptors in the pituitary gland and helps regulate prolactin release; a meta-analysis of randomised trials suggests it eases premenstrual symptoms such as breast tenderness, mood swings and irritability.

Dosage & how to use

Recommended dose20–40 mg of standardised dry extract daily (or 200–400 mg of fruit powder)
Best time to takeIn the morning on a near-empty stomach
FrequencyOnce daily, for at least 3 menstrual cycles

Best forms to choose

Standardised dry extract of chasteberry fruit (such as Ze 440 or BNO 1095), or fruit powder.

Important warnings

Not for use during pregnancy or breastfeeding

Avoid it with oestrogen-sensitive conditions or pituitary disorders

May cause mild nausea, headache or skin rash

Drug interactions

It may interfere with hormonal contraceptives and hormone therapy, and with drugs that act on dopamine (dopamine agonists such as bromocriptine, and antipsychotics).

View in the supplements guide

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Scientific references

  1. Verkaik S et al. Am J Obstet Gynecol 2017 (meta-analysis) — PMID: 28237870
  2. Rafieian-Kopaei M, Movahedi M. Electron Physician 2017 (systematic review) — PMID: 28243425
📚 Published sources and research: European Food Safety Authority (EFSA) • National Institutes of Health (NIH - ODS) • PubMed / Cochrane databases

Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)

⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.