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Riboflavin (Vitamin B2)

B vitamins & energy

Function & benefits

Riboflavin contributes to normal energy-yielding metabolism, the maintenance of normal vision, skin and mucous membranes, the protection of cells from oxidative stress and the reduction of tiredness and fatigue (EFSA-authorised claims); it is what turns urine bright yellow after taking it, which is normal and harmless.

Dosage & how to use

Recommended dose10–25 mg daily (the NRV is 1.4 mg; the high doses of 200–400 mg used in studies are for use under medical supervision only)
Best time to takeIn the morning with breakfast
FrequencyOnce daily

Best forms to choose

Pure riboflavin, or the active form riboflavin-5'-phosphate (R5P).

Important warnings

A very safe water-soluble vitamin; EFSA has set no upper limit because no adverse effects have been seen

Bright yellow urine is normal and nothing to worry about

Drug interactions

Tricyclic antidepressants, some antipsychotics (chlorpromazine) and the contraceptive pill may lower its levels in the body.

View in the supplements guide

Related supplements

Scientific references

  1. EFSA Journal 2010;8(10):1814 (riboflavin health claims)
  2. Boehnke C et al. Eur J Neurol 2004 — PMID: 15257686
📚 Published sources and research: European Food Safety Authority (EFSA) • National Institutes of Health (NIH - ODS) • PubMed / Cochrane databases

Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)

⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.