Pantothenic Acid (Vitamin B5)
B vitamins & energyFunction & benefits
Pantothenic acid contributes to normal energy-yielding metabolism, the reduction of tiredness and fatigue, normal mental performance, and the normal synthesis and metabolism of steroid hormones, vitamin D and some neurotransmitters (EFSA-authorised claims); it is part of coenzyme A (CoA), which burns carbohydrates and fats.
Dosage & how to use
| Recommended dose | 50–100 mg daily (the NRV on EU labels is 6 mg and the EFSA adequate intake for adults is 5 mg; doses up to 500 mg are used under professional supervision) |
| Best time to take | In the morning with breakfast |
| Frequency | Once daily |
Best forms to choose
Calcium D-pantothenate, or pantethine, the active form.
Important warnings
A very safe water-soluble vitamin that does not build up in the body; the excess leaves in urine
Very large doses (above 2000 mg) may cause loose stools
Drug interactions
No important drug interactions have been reported at the usual doses.
Related supplements
- Riboflavin (Vitamin B2)B vitamins & energy
- Thiamine (Vitamin B1) & BenfotiamineB vitamins & energy
- Niacin (Vitamin B3) — NicotinamideB vitamins & energy
- Folate (L-Methylfolate, Active Vitamin B9)B vitamins & energy
Scientific references
- EFSA Journal 2009;7(9):1218 (pantothenic acid and energy-yielding metabolism)
- EFSA Journal 2010;8(10):1758 (pantothenic acid, tiredness and steroid hormones)
- Yang M et al. Dermatol Ther (Heidelb) 2014 — PMID: 24831048
Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)
⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.