Bitter Melon Extract (Momordica charantia)
Metabolism & blood sugarFunction & benefits
A traditional Asian fruit containing charantin, vicine and insulin-like polypeptide-P; laboratory studies suggest it stimulates glucose uptake in muscle, but human evidence is still limited according to a Cochrane review.
Dosage & how to use
| Recommended dose | 500–1000 mg standardized extract |
| Best time to take | 30 minutes before main meals |
| Frequency | Twice daily |
Best forms to choose
Standardized extract capsules (2.5–5% charantin), avoiding the very bitter taste of the fruit.
Important warnings
Not for use during pregnancy or breastfeeding, as it may trigger uterine contractions and bleeding
Not for people with G6PD deficiency (favism), as the seeds contain vicine, which may cause haemolysis
Drug interactions
Critical interaction: it lowers glucose; do not use it with insulin or sulfonylureas without medical supervision, to avoid severe hypoglycaemia.
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Scientific references
- Ooi CP et al. Cochrane Database Syst Rev 2012 — PMID: 22895968
Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)
⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.