Natural Vitamin E (Mixed Tocopherols & Tocotrienols)

Antioxidants & cell protection

Function & benefits

The main fat-soluble antioxidant in cell membranes; vitamin E contributes to the protection of cells from oxidative stress (EFSA-authorised claim) by stopping chain reactions that oxidize unsaturated fats in the membranes.

Dosage & how to use

Recommended dose	100–200 IU (about 67–134 mg d-alpha-tocopherol)
Best time to take	With a main meal that contains fat
Frequency	Once daily

Best forms to choose

The natural form (d-alpha-tocopherol) with mixed tocopherols and tocotrienols; avoid the less effective synthetic form (dl-alpha-tocopherol).

Important warnings

The EFSA upper limit for adults is 300 mg a day (about 450 IU)

In a meta-analysis, high doses (400 IU or more) were linked to higher mortality, and they counteract vitamin K in blood clotting

Stop taking it two weeks before surgery

Drug interactions

Bleeding warning: it interacts with blood thinners and anticoagulants (warfarin, aspirin) and can cause bleeding at high doses.

View in the supplements guide

Related supplements

Scientific references

EFSA Journal 2010;8(10):1816 (vitamin E health claims)
NIH Office of Dietary Supplements (ODS): Vitamin E Fact Sheet
Miller ER 3rd et al. Ann Intern Med 2005 (meta-analysis) — PMID: 15537682

📚 Published sources and research: European Food Safety Authority (EFSA) • National Institutes of Health (NIH - ODS) • PubMed / Cochrane databases

Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)

⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.