Red Yeast Rice (Monacolin K < 3 mg)
Cholesterol & heart healthFunction & benefits
Rice fermented with the fungus Monascus purpureus, which produces monacolin K, an inhibitor of HMG-CoA reductase, the enzyme that makes cholesterol in the liver; a placebo-controlled trial and a JACC review suggest it supports normal total and LDL cholesterol levels.
Dosage & how to use
| Recommended dose | Less than 3 mg of monacolin K daily (the EU legal limit under Regulation (EU) 2022/860) |
| Best time to take | In the evening with dinner |
| Frequency | Once daily |
Best forms to choose
Red yeast rice extract standardised for monacolin K (less than 3 mg per daily portion) and tested free of citrinin.
Important warnings
Mandatory warnings (EU 2022/860): not for pregnant or breastfeeding women, people under 18 or people over 70
Do not use it with any other product containing red yeast rice, or with cholesterol-lowering medication
See a doctor if any health problem occurs, especially unexplained muscle pain or weakness
Drug interactions
Critical warning: never combine it with statins or fibrates. CYP3A4 inhibitors (grapefruit juice, clarithromycin, itraconazole, some HIV drugs) raise the risk of muscle damage.
Related supplements
- Plant Sterols & StanolsCholesterol & heart health
- Daily MultivitaminsGeneral health & immunity
- Omega-3 Fish OilGeneral & heart health
- Vitamin D3 (Cholecalciferol)General health & bones
Scientific references
- Commission Regulation (EU) 2022/860 (monacolins from red yeast rice)
- Heinz T et al. Nutr Res 2016 — PMID: 27865358
- Cicero AFG et al. J Am Coll Cardiol 2021 — PMID: 33538260
Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)
⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.