Pure MSM (Methylsulfonylmethane)
Joints & connective tissueFunction & benefits
An organic sulphur compound that supplies the sulphur needed for disulphide bonds in collagen and keratin fibres and supports connective tissue in cartilage and joints; studies suggest it moderates markers of oxidative stress after exercise.
Dosage & how to use
| Recommended dose | 1500–3000 mg daily; start with 1000 mg and build up gradually |
| Best time to take | With breakfast and lunch and a full glass of water |
| Frequency | Split into two doses |
Best forms to choose
Multi-stage distilled MSM powder or capsules (such as OptiMSM®) for guaranteed purity and freedom from heavy metals.
Important warnings
Safe up to 4 g a day
May cause gas or loose stools at first
Best avoided in the evening, as it can cause vivid dreams in some people
Drug interactions
No major drug interactions have been reported; take care with blood thinners at doses above 4 g.
Related supplements
- Glucosamine & Chondroitin ComplexBone & joint health
- Hydrolyzed Collagen PeptidesJoints & skin
- Calcium (Citrate / Carbonate)Bones & teeth
- Vitamin K2 (Menaquinone-7 / MK-7)Bones & blood vessels
Scientific references
- Withee ED et al. J Int Soc Sports Nutr 2017 — PMID: 28736511
Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)
⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.