Lemon Balm Leaf Extract (Melissa officinalis)
Stress & relaxationFunction & benefits
A lemon-scented herb of the mint family rich in rosmarinic acid; studies suggest it inhibits GABA transaminase, raising calming GABA in the brain, and soothes stress-related digestive cramps.
Dosage & how to use
| Recommended dose | 300–600 mg daily |
| Best time to take | With meals, or an hour before bed to support relaxation |
| Frequency | Split into 1–2 doses |
Best forms to choose
Leaf extract standardized for rosmarinic acid (at least 2–5%, such as Cyracos®), or leaf tea.
Important warnings
Take care if you have a severely underactive thyroid
Best to avoid concentrated supplements during pregnancy and breastfeeding
May cause mild drowsiness
Drug interactions
It may interfere with thyroid medication, as studies suggest it can inhibit the binding of thyroid-stimulating hormone (TSH) to its receptors. It strengthens sleeping pills and sedatives.
Related supplements
- Ashwagandha Root (KSM-66)Stress & relaxation
- Holy Basil Extract (Tulsi / Ocimum sanctum)Stress & relaxation
- Passionflower Extract (Passiflora incarnata)Stress & relaxation
- MelatoninSleep & relaxation
Scientific references
- European Medicines Agency (EMA): Community herbal monograph on Melissa officinalis L., folium
- Scholey A et al. Nutrients 2014 — PMID: 25360512
Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)
⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.