Pure Glycine Powder

Sleep & relaxation

Function & benefits

The simplest amino acid in nature; it acts as an inhibitory neurotransmitter and helps lower core body temperature by widening peripheral blood vessels, a physiological signal for deep sleep, and it makes up about a third of the collagen in joints and tendons.

Dosage & how to use

Recommended dose	3–5 g dissolved in a glass of water
Best time to take	An hour before bed
Frequency	Once daily

Best forms to choose

Pure free-form glycine powder of food-grade purity; it dissolves easily and tastes naturally sweet.

Important warnings

Very safe at the usual doses

May cause strong relaxation; do not take it during the day or before driving

Drug interactions

It may strengthen sedatives and anti-anxiety drugs and may reduce the effect of clozapine.

View in the supplements guide

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Scientific references

Bannai M, Kawai N. J Pharmacol Sci 2012 — PMID: 22293292

📚 Published sources and research: European Food Safety Authority (EFSA) • National Institutes of Health (NIH - ODS) • PubMed / Cochrane databases

Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)

⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.