Apigenin (Chamomile Extract)

Sleep & relaxation

Function & benefits

A plant flavonoid abundant in chamomile and parsley; it binds to GABA-A receptors in the nervous system, helping calm excessive nerve activity and supporting relaxation and restful sleep.

Dosage & how to use

Recommended dose	50–100 mg daily
Best time to take	30–60 minutes before bed
Frequency	Once daily

Best forms to choose

Standardized apigenin capsules (98% purity) extracted from chamomile flowers, or lipid extracts for better absorption.

Important warnings

Causes drowsiness; do not drive or operate machinery after taking it

Avoid concentrated doses during pregnancy and breastfeeding

Avoid it if you are allergic to chamomile or the daisy family

Drug interactions

It strengthens sedatives, sleeping pills and anti-anxiety drugs. It may slightly inhibit CYP2C9, so take care with warfarin and anticonvulsants.

View in the supplements guide

Related supplements

Scientific references

Salehi B et al. Int J Mol Sci 2019 (review) — PMID: 30875872

📚 Published sources and research: European Food Safety Authority (EFSA) • National Institutes of Health (NIH - ODS) • PubMed / Cochrane databases

Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)

⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.