WiBo Health

Lutein & Zeaxanthin (AREDS2 ratio)

Eye health & vision

Function & benefits

Yellow carotenoid pigments that concentrate in the macula and the lens of the eye; they act as a natural filter for high-energy blue light and help protect the photoreceptors from oxidative stress.

Dosage & how to use

Recommended dose10–20 mg lutein + 2–4 mg zeaxanthin daily
Best time to takeWith a meal that contains healthy fats such as olive oil or avocado
FrequencyOnce daily

Best forms to choose

Free lutein from marigold flowers with zeaxanthin in the 5:1 ratio used in the AREDS2 study.

Important warnings

Safe for long-term use

Continuous excessive doses may cause a slight yellow tint on the palms and soles, which is harmless and fades when the dose is reduced

Drug interactions

No major drug interactions have been reported; take it two hours apart from orlistat (a fat-absorption blocker) to ensure absorption.

View in the supplements guide

Related supplements

Scientific references

  1. AREDS2 Research Group. JAMA 2013 — PMID: 23644932
  2. NIH National Eye Institute: AREDS/AREDS2 clinical trials
📚 Published sources and research: European Food Safety Authority (EFSA) • National Institutes of Health (NIH - ODS) • PubMed / Cochrane databases

Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)

⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.