WiBo Health

D-Aspartic Acid (DAA)

Vitality & sports performance

Function & benefits

An isomer of aspartic acid concentrated in the pituitary gland and testes; studies suggest it stimulates luteinizing hormone (LH) release and may support testosterone synthesis in men with low levels, while its effect is temporary or absent in athletes with normal levels.

Dosage & how to use

Recommended dose3 g daily
Best time to takeIn the morning on an empty stomach with a glass of water
FrequencyIn cycles: 12–14 days on, then a full 2–3-week break

Best forms to choose

Pure D-aspartic acid powder, or formulas that combine it with zinc and vitamins B6, B12 and D3.

Important warnings

Sticking to on/off cycles is essential; continuous use for more than a month may lower hormone levels instead

Not for people under 18, women or pregnant women

Drug interactions

Safe with most medicines; do not combine it with testosterone replacement therapy (TRT) or oestrogen blockers.

View in the supplements guide

Related supplements

Scientific references

  1. Topo E et al. Reprod Biol Endocrinol 2009 — PMID: 19860889
📚 Published sources and research: European Food Safety Authority (EFSA) • National Institutes of Health (NIH - ODS) • PubMed / Cochrane databases

Content last updated: 17 October 2026 · Based on published sources and research (EFSA / NIH / PubMed)

⚖️ Medical disclaimer: The information and data provided here are for health education and nutritional guidance only. They are not a medical diagnosis and never replace a direct consultation with your doctor or pharmacist. Always consult your doctor before starting any supplement, especially during pregnancy or breastfeeding or when taking long-term medication.